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Channel: Pharmaceutical Intelligence » New England Journal of Medicine
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Foreseen changes in Guideline of Treatment of Cardiogenic Shock with...

Reporter: Aviva Lev-Ari, PhD, RN SHOCK II: IABP Use Questioned When myocardial infarction (MI) is complicated by cardiogenic shock, use of intraaortic balloon counterpulsation (IABP) did not reduce...

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Outcomes in High Cardiovascular Risk Patients: Prasugrel (Effient) vs....

Reporter and Curator: Aviva Lev-Ari, PhD, RN WOEST (What is the Optimal Antiplatelet and Anticoagulant Therapy in Patients with Oral Anticoagulantion and Coronary Stenting): Get Rid Of The Aspirin In...

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Will these findings impact the Clopidogrel market?

Reported by: Dr. Venkat S. Karra, Ph.D. Aspirin-clopidogrel combination no better than aspirin alone. Antiplatelet drugs such as aspirin are routinely prescribed to help prevent new strokes in people...

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Today’s fundamental challenge in Prostate cancer screening

Author: Dror Nir, PhD The management of men with prostate cancer is becoming one of the most challenging public health issues in the Western world. It is characterized by: over-diagnosis;...

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Artherogenesis: Predictor of CVD – the Smaller and Denser LDL Particles

Reporter: Aviva Lev-Ari, PhD, RN Updated 3/5/2013 Genetic Associations with Valvular Calcification and Aortic Stenosis N Engl J Med 2013; 368:503-512 February 7, 2013DOI: 10.1056/NEJMoa1109034 METHODS...

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PIK3CA mutation in Colorectal Cancer may serve as a Predictive Molecular...

Reporter: Aviva Lev-Ari, PhD, RN Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival N Engl J Med 2012; 367:1596-1606 October 25, 2012DOI: 10.1056/NEJMoa1207756 BACKGROUND Regular use of...

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Genome Sequencing of the Healthy

Genome Sequencing of the Healthy Curators: Larry H. Bernstein, MD, FCAP and Aviva Lev-Ari, PhD, RN   Key Issues in Genome Sequencing of Healthy Individuals Eric Topol, MD, Genomic Medicine I briefly...

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Lp(a) Gene Variant Association

Lp(a) Gene Variant Association Reporter: Larry H Bernstein, MD, FCAP Lp(a) Gene Variant Associated With Aortic Stenosis Reported by Lisa Nainggolan Feb 06, 2013; GThanassoulis et al. NEJM...

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Issues in Personalized Medicine in Cancer: Intratumor Heterogeneity and...

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing[1] Curator and Reporter: Stephen J. Williams, Ph.D. Genomic instability is considered a hallmark and necessary for...

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5th Annual Consumer Genetics Conference (CGC), September 25-27, 2013 Seaport...

Reporter: Aviva Lev-Ari, PhD, RN The Consumer Genetics Conference (CGC) is a one-of-a-kind event that draws together a dynamic community of scientists, clinicians, technology innovators, and patients...

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AHA, ACC Change in Requirement for Surgical Support for PCI Performance:...

AHA, ACC Change in Requirement for Surgical Support:  Class IIb -> Class III, Level of Evidence A: Supports Nonemergent PCI without Surgical Backup (Change of class IIb, level of Evidence B)....

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Do Novel Anticoagulants Affect the PT/INR? The Cases of XARELTO (rivaroxaban)...

Do Novel Anticoagulants Affect the PT/INR? The Cases of  XARELTO (rivaroxaban) or PRADAXA (dabigatran) Curators: Vivek Lal, MBBS, MD, FCIR, Justin D Pearlman, MD, PhD, FACC and Article Curator: Aviva...

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Treatment Options for Left Ventricular Failure – Temporary Circulatory...

Treatment Options for Left Ventricular Failure  -  Temporary Circulatory Support: Intra-aortic balloon pump (IABP) – Impella Recover LD/LP 5.0 and 2.5, Pump Catheters (Non-surgical) vs Bridge Therapy:...

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Developments in the Genomics and Proteomics of Type 2 Diabetes Mellitus and...

Larry H Bernstein, MD, FCAP, Reviewer and Curator...

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