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Issues in Personalized Medicine in Cancer: Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing[1] Curator and Reporter: Stephen J. Williams, Ph.D. Genomic instability is considered a hallmark and necessary for generating the mutations which drive tumorigenesis. Multiple studies had suggested that there may be multiple driver mutations and a plethora of passenger mutations driving a single tumor.  This diversity of […]

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